PSKH2

Across TCGA patient cohorts, PSKH2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,853 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PSKH2-associated GO terms across cancer lineages are Vesicle-mediated transport in synapse, Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors, and mRNA alternative polyadenylation. Each is linked with PSKH2 in more than 8 cancer types. Because this analysis shows association rather than direction, both PSKH2-to-partner and partner-to-PSKH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle-mediated transport in synapse grouped by PSKH2-low versus PSKH2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSKH2→partner) and Y-score (partner→PSKH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Vesicle-mediated transport in synapse →	+0.050	+0.057	<.001	<.001	3	9
ESCA	Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors →	+0.083	+0.116	<.001	.001	3	8
STAD	mRNA alternative polyadenylation →	+0.064	+0.054	<.001	<.001	3	8
STAD	Synaptic vesicle exocytosis →	+0.039	+0.054	<.001	<.001	3	8
STAD	mRNA 3'-end processing →	+0.087	+0.058	<.001	<.001	3	8
STAD	Telomere organization →	+0.079	+0.056	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,853 associations by consensus.

Vesicle-mediated transport in synapse by PSKH2 expression — STAD

Explore this box plot interactively →