PSKH2

Across TCGA patient cohorts, PSKH2 mutation is significantly associated with the RNA expression of many other genes, with 737 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSKH2-associated genes across cancer lineages are LINC02096, EIF1AY, and MSGN1. Each is linked with PSKH2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PSKH2-to-partner and partner-to-PSKH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02096 grouped by PSKH2-low versus PSKH2-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSKH2→partner) and Y-score (partner→PSKH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	LINC02096 →	+0.135	+3.065	<.001	.003	3	3
SKCM	EIF1AY →	+1.292	+2.006	.005	.005	3	3
SCLC	MSGN1 →	+0.327	+4.329	<.001	.006	3	2
HNSC	RNU6-302P →	+0.488	+3.716	<.001	.008	3	2
SKCM	ITGB1BP1 →	+0.443	+2.031	.001	.005	3	2
SKCM	ATP5IF1 →	+0.332	+2.044	.008	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 737 associations by consensus.

LINC02096 by PSKH2 expression — LUSC

Explore this box plot interactively →