PSKH2

Across TCGA cell cohorts, PSKH2 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible PSKH2-associated genes across cancer lineages are OR10J5, APOBEC1, and CLRN2. Each is linked with PSKH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSKH2-to-partner and partner-to-PSKH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10J5 grouped by PSKH2-low versus PSKH2-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSKH2→partner) and Y-score (partner→PSKH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR10J5 →	+0.071	+5.169	<.001	.005	3	2
BONE	APOBEC1 →	+0.026	+5.169	<.001	.004	3	1
BONE	CLRN2 →	+0.026	+5.169	<.001	.004	3	1
BONE	SCYGR8 →	+0.026	+5.169	<.001	.004	3	1
LARGE_INTESTINE	NAT8 →	+0.567	+3.443	.003	.009	3	1
LARGE_INTESTINE	OR10W1 →	+0.014	+3.562	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

OR10J5 by PSKH2 expression — BREAST

Explore this box plot interactively →