PSKH1

Across TCGA cell cohorts, PSKH1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PSKH1-associated genes across cancer lineages are RBMY1A1, ACTRT2, and NKX2-6. Each is linked with PSKH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSKH1-to-partner and partner-to-PSKH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMY1A1 grouped by PSKH1-low versus PSKH1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSKH1→partner) and Y-score (partner→PSKH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	RBMY1A1 →	+0.143	+5.807	<.001	.001	3	1
BLOOD_Leukemia	ACTRT2 →	+0.112	+4.922	<.001	.009	3	1
BLOOD_Leukemia	NKX2-6 →	+0.591	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.042	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

RBMY1A1 by PSKH1 expression — OVARY

Explore this box plot interactively →