PSIP1P1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, PSIP1P1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated PSIP1P1 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher PSIP1P1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PSIP1P1 expression acts as an unfavorable survival marker, although some lineages such as READ and KIRC show a favorable association.

READ, LIHC, and KIRC are the cancer types where PSIP1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
READDFSTertileAll0.7510.364.00155view →
LIHCOSTertileII,III,IV0.5120.772<.00148view →
KIRCDFSTertileAll0.7540.479<.00141view →
ACCOSMedianAll0.4650.754.00341view →
KICHDFSMedianIII,IV0.2750.861.00240view →
UCECOSTertileAll0.8940.946.00238view →
MESODFSMedianIV0.2110.466.01533view →
UCSDFSTertileIV0.9810.401.02430view →
LUSCOSQuartileAll0.8630.749.00127view →
CESCOSTertileII,III,IV0.9000.670.00726view →
CHOLDFSQuartileII,III,IV1.0000.135.00525view →
LUADDFSMedianIV0.7770.212.00118view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

PSIP1P1–READ (DFS)

Kaplan–Meier survival curve for PSIP1P1 RNA-high vs -low samples in READ.

Open the READ breakdown →

Exploration