PSIP1

Across TCGA patient cohorts, PSIP1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,994 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PSIP1-associated genes across cancer lineages are CNTLN, TXNDC16, and RCL1. Each is linked with PSIP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PSIP1-to-partner and partner-to-PSIP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSIP1 versus CNTLN in GBM, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSIP1→partner) and Y-score (partner→PSIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CNTLN →	+0.751	+0.610	<.001	<.001	3	8
GBM	TXNDC16 →	+0.714	+0.681	<.001	<.001	3	8
BRCA	RCL1 →	+0.791	+0.653	<.001	<.001	3	8
HNSC	SP4 →	+0.804	+0.499	<.001	<.001	3	7
OV	UHRF2 →	+0.597	+0.645	.008	<.001	3	7
HNSC	SNAPC3 →	+0.716	+0.599	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,994 associations by consensus.

PSIP1 vs CNTLN — GBM

Explore this scatter interactively →