PSIP1

Across TCGA cell cohorts, PSIP1 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PSIP1-associated genes across cancer lineages are OR10W1, OR2L8, and CD207. Each is linked with PSIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSIP1-to-partner and partner-to-PSIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by PSIP1-low versus PSIP1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSIP1→partner) and Y-score (partner→PSIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR10W1 →	+0.021	+4.643	<.001	<.001	3	2
LUNG_NSCLC_LUAD	OR2L8 →	+0.015	+5.266	<.001	.001	3	2
BLOOD_Lymphoma	CD207 →	+0.119	+3.491	.001	.009	3	1
BLOOD_Lymphoma	CASQ2 →	+0.082	+3.956	.001	.002	3	1
BLOOD_Lymphoma	PDCL2 →	+0.314	+3.192	<.001	.008	3	1
BLOOD_Lymphoma	COL6A5 →	+1.584	+3.579	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

OR10W1 by PSIP1 expression — BLOOD_Lymphoma

Explore this box plot interactively →