Across TCGA patient cohorts, PSG7 mutation is significantly associated with the RNA expression of many other genes, with 921 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSG7-associated genes across cancer lineages are RNU6-271P, RNA5SP323, and RN7SKP262. Each is linked with PSG7 in more than 2 cancer types. Because this analysis shows association rather than direction, both PSG7-to-partner and partner-to-PSG7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSG7→partner) and Y-score (partner→PSG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-271P →	+0.243	+4.339	<.001	.007	3	3
PRAD	RNA5SP323 →	+0.378	+4.669	<.001	.004	3	3
BRCA	RN7SKP262 →	+0.269	+6.586	<.001	<.001	3	3
BRCA	USP17L14P →	+0.025	+5.016	<.001	.005	3	3
UCEC	CCDC102A →	-0.517	-3.437	.002	.005	3	3
UCEC	ANKRD45 →	-0.938	-3.783	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 921 associations by consensus.

Exploration

PSG7 survival (RNA) · tumor vs normal (RNA) · all PSG7 data types