PSG7

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PSG7 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSG7-associated genes across cancer lineages are ASNS, AMPK_alpha, and ATM. Each is linked with PSG7 in more than 2 cancer types. Because this analysis shows association rather than direction, both PSG7-to-partner and partner-to-PSG7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSG7→partner) and Y-score (partner→PSG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADASNS →+0.627+3.008.002.01933
SKCMAMPK_alpha →+0.122+1.054.002.02733
UCECATM →-0.433-3.169.034.01932
SKCMPI3K-p85 →+0.137+2.115.023.01532
SKCMAnnexin-1 →+0.363+1.678.005.01832
LUSCG6PD →+0.990+2.816<.001.03631
Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration