Across TCGA patient cohorts, PSG3 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSG3-associated genes across cancer lineages are 14-3-3_epsilon, ATM, and c-Kit. Each is linked with PSG3 in more than 2 cancer types. Because this analysis shows association rather than direction, both PSG3-to-partner and partner-to-PSG3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSG3→partner) and Y-score (partner→PSG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	14-3-3_epsilon →	+0.123	+2.834	.018	.035	3	3
UCEC	ATM →	-0.530	-2.000	.002	.010	3	2
UCEC	c-Kit →	-0.224	-2.680	.014	.006	3	2
SKCM	SCD →	+0.166	+2.220	.002	.030	3	2
SKCM	TFRC →	+0.489	+2.459	.021	.017	3	2
LUAD	Acetyl-a-Tubulin-Lys40 →	+0.530	+3.584	.047	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

PSG3 survival (RNA) · tumor vs normal (RNA) · all PSG3 data types