Across TCGA cell cohorts, PSG3 mutation is significantly associated with the RNA expression of many other genes, with 54 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PSG3-associated genes across cancer lineages are MED31, NDUFA8, and HAUS8. Each is linked with PSG3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSG3-to-partner and partner-to-PSG3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSG3→partner) and Y-score (partner→PSG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MED31 →	+0.713	+3.212	.002	.006	3	1
LARGE_INTESTINE	NDUFA8 →	+0.461	+3.212	.008	.006	3	1
LARGE_INTESTINE	HAUS8 →	+0.480	+3.212	.009	.006	3	1
LARGE_INTESTINE	UQCC2 →	+0.708	+3.299	<.001	.004	3	1
LARGE_INTESTINE	WRAP53 →	+0.574	+3.212	.004	.006	3	1
LARGE_INTESTINE	C1orf162 →	+0.249	+3.385	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

Exploration

PSG3 survival (RNA) · tumor vs normal (RNA) · all PSG3 data types