Across TCGA cell cohorts, PSG3 mutation is significantly associated with the mutation status of many other genes, with 3,687 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PSG3-associated genes across cancer lineages are KHSRP, SRCIN1, and H6PD. Each is linked with PSG3 in more than 2 cancer types. Because this analysis shows association rather than direction, both PSG3-to-partner and partner-to-PSG3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSG3→partner) and Y-score (partner→PSG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KHSRP →	+2.369	+2.471	.005	.005	1	3
LARGE_INTESTINE	SRCIN1 →	+1.632	+3.000	.001	.001	1	3
BLOOD_Leukemia	H6PD →	+2.975	+3.794	.006	.006	1	3
LUNG_NSCLC_LUAD	GJA8 →	+3.000	+3.662	.007	.007	1	3
LUNG_NSCLC_LUAD	SACS →	+2.093	+3.796	.008	.008	1	3
LARGE_INTESTINE	LAMB3 →	+1.895	+2.392	.006	.006	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,687 associations by consensus.

Exploration

PSG3 survival (RNA) · tumor vs normal (RNA) · all PSG3 data types