PSG2

Across TCGA cell cohorts, PSG2 mutation is significantly associated with the drug of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PSG2-associated genes across cancer lineages are IC-87114, BDF00022089a, and CZC24832. Each is linked with PSG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSG2-to-partner and partner-to-PSG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IC-87114 grouped by PSG2-low versus PSG2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSG2→partner) and Y-score (partner→PSG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	IC-87114 →	+0.227	+2.652	.028	.045	3	1
LARGE_INTESTINE	BDF00022089a →	+0.327	+2.649	.035	.046	2	1
LARGE_INTESTINE	CZC24832 →	+0.279	+2.646	.032	.047	2	1
LARGE_INTESTINE	Picolinici-acid →	+0.313	+2.646	.032	.047	2	1
LARGE_INTESTINE	BDOCA000347a →	+0.353	+2.649	.033	.046	1	1
LARGE_INTESTINE	AGI-6780 →	+0.401	+2.646	.038	.047	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

IC-87114 by PSG2 expression — LARGE_INTESTINE

Explore this box plot interactively →