PSG11

Across TCGA pan-cancer cohorts, PSG11 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated PSG11 data layer compared with 6 for mutation status.

The strongest signal is observed in small cell lung cancer (SCLC), where higher PSG11 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PSG11 expression acts as an unfavorable survival marker, although some lineages such as ACC and ESCA show a favorable association.

SCLC, KIRC, and BRCA are the cancer types where PSG11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Tertile	II,III,IV	0.164	0.819	<.001	81	view →
KIRC	DFS	Tertile	III,IV	0.509	0.677	.006	63	view →
BRCA	DFS	Tertile	All	0.439	0.541	.009	54	view →
THCA	DFS	Tertile	All	0.864	0.948	<.001	42	view →
LGG	DFS	Tertile	All	0.223	0.442	<.001	24	view →
READ	OS	Tertile	IV	0.649	0.924	.025	21	view →
STAD	DFS	Median	All	0.236	0.492	.015	15	view →
OV	OS	Tertile	IV	0.610	0.768	.033	14	view →
ACC	DFS	Tertile	IV	0.602	0.254	.033	13	view →
TGCT	OS	Quartile	II,III,IV	0.670	1.000	.014	12	view →
ESCA	OS	Quartile	III,IV	0.679	0.300	.004	12	view →
MESO	OS	Tertile	All	0.383	0.571	.044	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

PSG11–SCLC (OS)

Open the SCLC breakdown →