PSD3

Across TCGA pan-cancer cohorts, PSD3 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated PSD3 data layer compared with 27 for mass-spec protein and 11 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PSD3 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PSD3 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

CCRCC, HNSC, and OV are the cancer types where PSD3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	1.000	0.632	.003	17	view →
HNSC	DFS	Tertile	IV	0.590	0.895	.011	7	view →
OV	DFS	Median	All	0.777	1.000	.040	4	view →
LUAD	DFS	Quartile	III,IV	0.357	0.875	.027	4	view →
LSCC	OS	Median	All	0.932	0.814	.026	3	view →
UCEC	DFS	Tertile	All	1.000	0.923	.040	2	view →
GBM	OS	Quartile	All	0.323	0.511	.030	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

PSD3–CCRCC (DFS)

Open the CCRCC breakdown →