PSD3

Across TCGA cell cohorts, PSD3 mutation is significantly associated with the RNA expression of many other genes, with 535 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PSD3-associated genes across cancer lineages are BCAS2, UTP11, and LIN52. Each is linked with PSD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSD3-to-partner and partner-to-PSD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BCAS2 grouped by PSD3-low versus PSD3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSD3→partner) and Y-score (partner→PSD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BCAS2 →	+0.573	+3.064	.001	.009	3	2
LARGE_INTESTINE	UTP11 →	+0.589	+3.364	.002	.002	3	2
LARGE_INTESTINE	LIN52 →	+0.755	+3.364	<.001	.002	3	2
LARGE_INTESTINE	CBARP →	+0.933	+3.169	<.001	.009	3	2
SOFT_TISSUE	KRTAP4-6 →	+0.107	+5.369	<.001	.004	3	1
OESOPHAGUS	KRTAP10-3 →	+0.030	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 535 associations by consensus.

BCAS2 by PSD3 expression — LARGE_INTESTINE

Explore this box plot interactively →