PSD

Across TCGA cell cohorts, PSD RNA expression is significantly associated with the go_rna of many other GO terms, with 4,295 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PSD-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, tRNA transcription, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with PSD in more than 14 cancer types. Because this analysis shows association rather than direction, both PSD-to-partner and partner-to-PSD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by PSD-low versus PSD-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSD→partner) and Y-score (partner→PSD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.190	+1.016	<.001	<.001	3	15
BONE	tRNA transcription →	+0.173	+2.067	<.001	<.001	3	14
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.140	+0.759	<.001	.001	3	14
STOMACH	Protein sumoylation →	+0.078	+1.463	.005	.009	3	14
OESOPHAGUS	Regulation of myoblast fusion →	+0.176	+0.933	<.001	.001	3	14
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.167	+0.810	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,295 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by PSD expression — URINARY_TRACT

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