PSAT1P2

Across TCGA pan-cancer cohorts, PSAT1P2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of PSAT1P2’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where PSAT1P2 RNA is repressed in tumor relative to normal tissue. In most cancer types PSAT1P2 is over-expressed in tumor, although a few such as HNSC and THCA show the opposite, repressed pattern.

HNSC and THCA are the cancer types where PSAT1P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PSAT1P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	−0.031	.011	4	view →
THCA	All	III,IV	−0.026	.042	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

PSAT1P2–HNSC

Open the HNSC breakdown →