PSAT1

Across TCGA patient cohorts, PSAT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,514 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSAT1-associated proteins across cancer lineages are ASNS, MTHFD2, and NOP2. Each is linked with PSAT1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PSAT1-to-partner and partner-to-PSAT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSAT1 versus ASNS in BRCA, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PSAT1→partner) and Y-score (partner→PSAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ASNS →	+0.977	+2.265	<.001	<.001	3	8
UCEC	MTHFD2 →	+0.753	+1.254	<.001	<.001	3	8
BRCA	NOP2 →	+0.512	+1.855	<.001	<.001	3	8
BRCA	DDX21_S89 →	+1.005	+2.111	<.001	<.001	3	7
BRCA	DLGAP4_T915 →	+0.845	+1.933	<.001	<.001	3	7
LSCC	DNMT1_S714 →	+0.702	+0.956	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,514 associations by consensus.

PSAT1 vs ASNS — BRCA

Explore this scatter interactively →