PSAPL1

Across TCGA cell cohorts, PSAPL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 287 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PSAPL1-associated GO terms across cancer lineages are RNA stabilization, Adenylate cyclase-modulating G protein-coupled receptor signaling pathway, and Astral microtubule organization. Each is linked with PSAPL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PSAPL1-to-partner and partner-to-PSAPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA stabilization grouped by PSAPL1-low versus PSAPL1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSAPL1→partner) and Y-score (partner→PSAPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	RNA stabilization →	+0.054	+1.218	.003	.007	3	5
UPPER_AERODIGESTIVE_TRACT	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.050	-0.641	.006	.006	2	5
UPPER_AERODIGESTIVE_TRACT	Astral microtubule organization →	+0.122	+0.870	<.001	.006	3	3
UPPER_AERODIGESTIVE_TRACT	Positive regulation of striated muscle contraction →	-0.153	-0.744	.004	.001	3	3
STOMACH	Cell junction assembly →	+0.046	+0.795	.007	.005	3	3
LUNG_NSCLC_LUAD	Regulation of post-translational protein modification →	+0.030	+0.398	.007	.005	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 287 associations by consensus.

RNA stabilization by PSAPL1 expression — OESOPHAGUS

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