Across TCGA patient cohorts, PSAP protein abundance is significantly associated with the RNA expression of many other genes, with 12,365 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSAP-associated genes across cancer lineages are FCGR1A, HTRA4, and FCGR1B. Each is linked with PSAP in more than 7 cancer types. Because this analysis shows association rather than direction, both PSAP-to-partner and partner-to-PSAP results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSAP→partner) and Y-score (partner→PSAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FCGR1A →	+1.097	+0.630	<.001	<.001	3	8
LSCC	HTRA4 →	+0.831	+0.408	<.001	<.001	3	8
GBM	FCGR1B →	+0.610	+0.343	<.001	<.001	3	8
GBM	CTSZ →	+0.991	+0.576	.001	<.001	3	7
HNSC	APOC1 →	+1.816	+0.233	<.001	<.001	3	7
UCEC	FCER1G →	+1.221	+0.326	<.001	.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,365 associations by consensus.

Exploration

PSAP survival (RNA) · tumor vs normal (RNA) · all PSAP data types