PRXL2CP1

Across TCGA pan-cancer cohorts, PRXL2CP1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of PRXL2CP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where PRXL2CP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PRXL2CP1 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

HNSC, READ, and THCA are the cancer types where PRXL2CP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PRXL2CP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.018	.024	3	view →
READ	All	All	+0.122	.010	2	view →
THCA	All	All	−0.028	.012	2	view →
KIRC	Male	All	+0.020	.013	2	view →
LUSC	Male	All	−0.016	.013	2	view →
KIRP	Male	All	−0.020	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

PRXL2CP1–HNSC

Open the HNSC breakdown →