PRXL2C

Across TCGA patient cohorts, PRXL2C protein abundance is significantly associated with the RNA expression of many other genes, with 2,714 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PRXL2C-associated genes across cancer lineages are SHISA3, FHL5, and PCOLCE2. Each is linked with PRXL2C in more than 2 cancer types. Because this analysis shows association rather than direction, both PRXL2C-to-partner and partner-to-PRXL2C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRXL2C versus SHISA3 in OV, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRXL2C→partner) and Y-score (partner→PRXL2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SHISA3 →	+1.016	+0.524	.008	.001	3	3
UCEC	FHL5 →	+0.754	+0.401	.003	<.001	3	2
BRCA	PCOLCE2 →	+2.101	+0.530	<.001	<.001	3	2
BRCA	ASS1P11 →	+0.487	+0.255	<.001	.006	3	2
HNSC	COL4A2-AS1 →	+0.778	+0.482	.001	.007	3	2
BRCA	EIF4BP8 →	+0.374	+0.301	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,714 associations by consensus.

PRXL2C vs SHISA3 — OV

Explore this scatter interactively →