PRXL2C

Across TCGA patient cohorts, PRXL2C mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRXL2C-associated genes across cancer lineages are Mast cells and Macrophages M2. Each is linked with PRXL2C in more than 1 cancer types. Because this analysis shows association rather than direction, both PRXL2C-to-partner and partner-to-PRXL2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mast cells grouped by PRXL2C-low versus PRXL2C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRXL2C→partner) and Y-score (partner→PRXL2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Mast cells →	+0.021	+2.850	.033	.035	3	1
UCEC	Macrophages M2 →	+0.023	+2.925	<.001	.031	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Mast cells by PRXL2C expression — UCEC

Explore this box plot interactively →