PRXL2C

Across TCGA cell cohorts, PRXL2C RNA expression is significantly associated with the go_rna of many other GO terms, with 5,494 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PRXL2C-associated GO terms across cancer lineages are PML body organization, Positive regulation of supramolecular fiber organization, and Cytotoxic T cell degranulation. Each is linked with PRXL2C in more than 15 cancer types. Because this analysis shows association rather than direction, both PRXL2C-to-partner and partner-to-PRXL2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PML body organization grouped by PRXL2C-low versus PRXL2C-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRXL2C→partner) and Y-score (partner→PRXL2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	PML body organization →	+0.168	+0.703	<.001	<.001	3	16
BREAST	Positive regulation of supramolecular fiber organization →	+0.081	+1.029	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Cytotoxic T cell degranulation →	-0.388	-1.022	<.001	.001	3	10
LUNG_NSCLC_LUSC	Positive regulation of cytoskeleton organization →	+0.071	+0.981	.001	.001	3	10
BONE	Positive regulation of focal adhesion assembly →	+0.173	+1.202	.002	<.001	3	10
BONE	Regulation of interleukin-6-mediated signaling pathway →	+0.283	+0.996	.006	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,494 associations by consensus.

PML body organization by PRXL2C expression — OVARY

Explore this box plot interactively →