PRUNEP1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PRUNEP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 2,761 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRUNEP1-associated proteins across cancer lineages are VIM_Y53, BCAR3_S338, and HABP4_S7. Each is linked with PRUNEP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRUNEP1-to-partner and partner-to-PRUNEP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRUNEP1 versus VIM_Y53 in OV, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRUNEP1→partner) and Y-score (partner→PRUNEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVVIM_Y53 →+0.719+0.242<.001.00532
OVBCAR3_S338 →-0.617-0.111.005.00132
LSCCHABP4_S7 →-0.363-0.058.004.00632
LSCCARFGEF3_S1991 →+0.462+0.104.003<.00132
HNSCPALLD_Y438 →-0.778-0.166.004.00732
PDACTTL →-0.345-0.066.003.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,761 associations by consensus.

PRUNEP1 vs VIM_Y53 — OV

Per-sample scatter of PRUNEP1 vs VIM_Y53 in OV (Pearson r = 0.66).

Explore this scatter interactively →

Exploration