PRUNEP1

Across TCGA patient cohorts, PRUNEP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,163 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRUNEP1-associated GO terms across cancer lineages are Telomere maintenance, RNA 3'-end processing, and Regulation of DNA replication. Each is linked with PRUNEP1 in more than 10 cancer types. Because this analysis shows association rather than direction, both PRUNEP1-to-partner and partner-to-PRUNEP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere maintenance grouped by PRUNEP1-low versus PRUNEP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRUNEP1→partner) and Y-score (partner→PRUNEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Telomere maintenance →	+0.067	+0.089	<.001	<.001	3	11
STAD	RNA 3'-end processing →	+0.069	+0.093	<.001	<.001	3	10
STAD	Regulation of DNA replication →	+0.063	+0.076	<.001	<.001	3	10
STAD	Maintenance of cell number →	+0.057	+0.082	<.001	<.001	3	9
STAD	Regulation of reactive oxygen species metabolic process →	+0.052	+0.098	<.001	<.001	3	9
STAD	Regulation of double-strand break repair via homologous recombination →	+0.059	+0.088	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,163 associations by consensus.

Telomere maintenance by PRUNEP1 expression — STAD

Explore this box plot interactively →