Across TCGA patient cohorts, PRTN3 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRTN3-associated genes across cancer lineages are MIR3692, RN7SL134P, and MIR154. Each is linked with PRTN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRTN3-to-partner and partner-to-PRTN3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRTN3→partner) and Y-score (partner→PRTN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR3692 →	+0.418	+5.292	.004	.002	3	2
UCEC	RN7SL134P →	+0.356	+4.184	<.001	.003	3	1
LUSC	MIR154 →	+0.338	+7.924	<.001	.008	3	1
UCEC	RNA5SP319 →	+0.750	+4.061	<.001	.005	3	1
UCEC	RNU1-17P →	+0.389	+4.520	<.001	.001	3	1
UCEC	SNORD90 →	+0.527	+3.840	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

PRTN3 survival (RNA) · tumor vs normal (RNA) · all PRTN3 data types