PRTFDC1

Across TCGA patient cohorts, PRTFDC1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,739 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PRTFDC1-associated genes across cancer lineages are ARHGAP21, PARD3, and THNSL1. Each is linked with PRTFDC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PRTFDC1-to-partner and partner-to-PRTFDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRTFDC1 versus ARHGAP21 in BRCA, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRTFDC1→partner) and Y-score (partner→PRTFDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARHGAP21 →	+0.541	+0.540	<.001	<.001	3	5
HNSC	PARD3 →	+1.238	+0.549	<.001	.004	3	5
BRCA	THNSL1 →	+0.829	+0.801	<.001	<.001	3	5
HNSC	SLC29A2 →	+0.929	+0.514	<.001	<.001	3	5
OV	PHGDH →	+1.163	+0.750	<.001	<.001	3	5
LSCC	ANKRD26 →	+0.559	+0.618	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,739 associations by consensus.

PRTFDC1 vs ARHGAP21 — BRCA

Explore this scatter interactively →