PRTFDC1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PRTFDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,829 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PRTFDC1-associated GO terms across cancer lineages are Neuron projection arborization, Negative regulation of leukocyte chemotaxis, and Positive regulation of smooth muscle cell chemotaxis. Each is linked with PRTFDC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PRTFDC1-to-partner and partner-to-PRTFDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neuron projection arborization grouped by PRTFDC1-low versus PRTFDC1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRTFDC1→partner) and Y-score (partner→PRTFDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINNeuron projection arborization →+0.094+1.317<.001<.00136
OESOPHAGUSNegative regulation of leukocyte chemotaxis →-0.190-2.098<.001.00636
BREASTPositive regulation of smooth muscle cell chemotaxis →+0.935+1.522<.001.00827
OVARYProtein localization to nuclear inner membrane →+0.103+1.906.003<.00136
BREASTNegative regulation of cellular senescence →+0.088+1.978.003.00136
BREASTPositive regulation of axon extension →+0.129+2.296<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,829 associations by consensus.

Neuron projection arborization by PRTFDC1 expression — SKIN

Box plot of Neuron projection arborization in PRTFDC1-low vs PRTFDC1-high samples in SKIN.

Explore this box plot interactively →

Exploration