Across TCGA patient cohorts, PRSS57 protein abundance is significantly associated with the RNA expression of many other genes, with 1,948 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PRSS57-associated genes across cancer lineages are FPR2, MEFV, and CSF3R. Each is linked with PRSS57 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRSS57-to-partner and partner-to-PRSS57 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS57→partner) and Y-score (partner→PRSS57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	FPR2 →	+3.265	+1.840	.001	.002	3	4
PDAC	MEFV →	+2.253	+2.159	<.001	.004	3	3
PDAC	CSF3R →	+2.437	+1.817	.001	.002	3	3
COAD	BCL2A1 →	+2.665	+2.350	.002	.001	3	3
COAD	CLEC4D →	+1.203	+2.408	.002	.002	3	3
COAD	CXCL8 →	+3.591	+2.145	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,948 associations by consensus.

Exploration

PRSS57 survival (RNA) · tumor vs normal (RNA) · all PRSS57 data types