Across TCGA cell cohorts, PRSS57 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,264 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRSS57-associated GO terms across cancer lineages are Negative regulation of translational initiation, Negative regulation of myoblast fusion, and Negative regulation of mRNA processing. Each is linked with PRSS57 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRSS57-to-partner and partner-to-PRSS57 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS57→partner) and Y-score (partner→PRSS57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of translational initiation →	+0.083	+0.098	.001	.001	3	8
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.171	+0.191	<.001	<.001	3	6
OESOPHAGUS	Negative regulation of mRNA processing →	+0.122	+0.136	<.001	.004	3	6
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.141	+0.172	<.001	.001	3	6
OESOPHAGUS	Regulation of translational initiation →	+0.097	+0.193	<.001	<.001	3	6
STOMACH	Regulation of sphingolipid biosynthetic process →	+0.081	+0.104	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,264 associations by consensus.

Exploration

PRSS57 survival (RNA) · tumor vs normal (RNA) · all PRSS57 data types