PRSS56

Across TCGA patient cohorts, PRSS56 protein abundance is significantly associated with the RNA expression of many other genes, with 720 significant associations in total. OV shows the largest number of these associations.

The most reproducible PRSS56-associated genes across cancer lineages are RNU6-558P, SNRPEP5, and ADGRL3-AS1. Each is linked with PRSS56 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRSS56-to-partner and partner-to-PRSS56 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRSS56 versus RNU6-558P in LUAD, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS56→partner) and Y-score (partner→PRSS56) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-558P →	+0.815	+2.458	<.001	<.001	3	1
LUAD	SNRPEP5 →	+0.775	+2.458	.005	<.001	3	1
LUAD	ADGRL3-AS1 →	+0.114	+2.458	<.001	<.001	3	1
LUAD	RNU6-1092P →	+0.929	+2.458	<.001	<.001	3	1
LUAD	SALL1 →	+4.093	+2.377	<.001	<.001	1	2
LUAD	IQCE →	+1.226	+2.359	.008	<.001	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 720 associations by consensus.

PRSS56 vs RNU6-558P — LUAD

Explore this scatter interactively →