PRSS53

Across TCGA patient cohorts, PRSS53 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,720 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRSS53-associated proteins across cancer lineages are HID1, PLOD2, and SEC23B. Each is linked with PRSS53 in more than 5 cancer types. Because this analysis shows association rather than direction, both PRSS53-to-partner and partner-to-PRSS53 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRSS53 versus HID1 in OV, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS53→partner) and Y-score (partner→PRSS53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HID1 →	-0.508	-0.232	.002	.003	3	6
CCRCC	PLOD2 →	+1.169	+0.653	<.001	<.001	3	6
OV	SEC23B →	-0.331	-0.315	<.001	<.001	3	5
LSCC	BCL2L14_S44 →	-1.532	-0.412	<.001	<.001	3	4
PDAC	CLYBL →	-0.489	-0.241	<.001	<.001	3	4
UCEC	DENND2D →	-0.321	-0.361	.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,720 associations by consensus.

PRSS53 vs HID1 — OV

Explore this scatter interactively →