PRSS46P

Across TCGA patient cohorts, PRSS46P RNA expression is significantly associated with the go_rna of many other GO terms, with 7,133 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRSS46P-associated GO terms across cancer lineages are Nucleotide-excision repair, Vacuolar transport, and Nuclear-transcribed mRNA catabolic process. Each is linked with PRSS46P in more than 27 cancer types. Because this analysis shows association rather than direction, both PRSS46P-to-partner and partner-to-PRSS46P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleotide-excision repair grouped by PRSS46P-low versus PRSS46P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS46P→partner) and Y-score (partner→PRSS46P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Nucleotide-excision repair →	+0.052	+0.207	<.001	<.001	3	28
STAD	Vacuolar transport →	+0.062	+0.205	<.001	<.001	3	28
ESCA	Nuclear-transcribed mRNA catabolic process →	+0.077	+0.355	<.001	<.001	3	28
ESCA	Peptidyl-lysine modification →	+0.063	+0.385	<.001	<.001	3	28
STAD	Positive regulation of amide metabolic process →	+0.066	+0.193	<.001	<.001	3	28
STAD	Autophagosome organization →	+0.057	+0.190	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,133 associations by consensus.

Nucleotide-excision repair by PRSS46P expression — STAD

Explore this box plot interactively →