Across TCGA patient cohorts, PRSS41 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,828 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PRSS41-associated GO terms across cancer lineages are Monosaccharide metabolic process, Membrane disassembly, and Positive regulation of protein ubiquitination. Each is linked with PRSS41 in more than 11 cancer types. Because this analysis shows association rather than direction, both PRSS41-to-partner and partner-to-PRSS41 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS41→partner) and Y-score (partner→PRSS41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Monosaccharide metabolic process →	+0.049	+0.642	<.001	<.001	3	12
STAD	Membrane disassembly →	+0.087	+0.735	<.001	<.001	3	10
KIRC	Positive regulation of protein ubiquitination →	+0.027	+0.088	<.001	<.001	3	10
KIRC	Methylation →	+0.029	+0.104	<.001	<.001	3	10
TGCT	Negative regulation of DNA-templated transcription, elongation →	+0.047	+1.080	<.001	<.001	2	11
ESCA	Negative regulation of RNA splicing →	+0.060	+0.383	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,828 associations by consensus.

Exploration

PRSS41 survival (RNA) · tumor vs normal (RNA) · all PRSS41 data types