PRSS3

Across TCGA patient cohorts, PRSS3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,165 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRSS3-associated proteins across cancer lineages are RPS8_T130, ZYX_S143, and ZDHHC5_S621. Each is linked with PRSS3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRSS3-to-partner and partner-to-PRSS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRSS3 versus RPS8_T130 in HNSC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS3→partner) and Y-score (partner→PRSS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPS8_T130 →	+0.608	+1.325	.001	.001	3	4
PDAC	ZYX_S143 →	-0.790	-1.720	<.001	.001	3	3
HNSC	ZDHHC5_S621 →	+0.671	+1.738	.004	.001	3	3
BRCA	VPS11 →	-0.161	-0.633	<.001	.001	3	3
UCEC	ARFIP1 →	-0.372	-1.320	<.001	<.001	3	3
COAD	ORC4 →	+0.317	+0.523	<.001	.003	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,165 associations by consensus.

PRSS3 vs RPS8_T130 — HNSC

Explore this scatter interactively →