PRSS3

Across TCGA patient cohorts, PRSS3 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible PRSS3-associated genes across cancer lineages are GMP and Basophils. Each is linked with PRSS3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRSS3-to-partner and partner-to-PRSS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by PRSS3-low versus PRSS3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS3→partner) and Y-score (partner→PRSS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GMP →	+0.034	+1.735	.003	.043	3	1
UCEC	Basophils →	+0.243	+3.169	.009	.020	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GMP by PRSS3 expression — SKCM

Explore this box plot interactively →