PRSS3

Across TCGA cell cohorts, PRSS3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,909 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible PRSS3-associated GO terms across cancer lineages are Positive regulation of adiponectin secretion, Luteinizing hormone signaling pathway, and Positive regulation of transmission of nerve impulse. Each is linked with PRSS3 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRSS3-to-partner and partner-to-PRSS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of adiponectin secretion grouped by PRSS3-low versus PRSS3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS3→partner) and Y-score (partner→PRSS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of adiponectin secretion →	+1.107	+2.835	<.001	<.001	3	8
LARGE_INTESTINE	Luteinizing hormone signaling pathway →	+1.007	+2.525	.001	<.001	3	8
OVARY	Positive regulation of transmission of nerve impulse →	+1.540	+2.795	<.001	<.001	3	8
STOMACH	Positive regulation of sodium ion transmembrane transport →	+0.207	+3.624	<.001	<.001	3	8
OVARY	Negative regulation of small GTPase mediated signal transduction →	+0.065	+2.279	.001	.004	3	7
LUNG_NSCLC_LUAD	Podocyte development →	+0.194	+1.462	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,909 associations by consensus.

Positive regulation of adiponectin secretion by PRSS3 expression — OVARY

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