PRSS27

Across TCGA patient cohorts, PRSS27 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,974 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRSS27-associated proteins across cancer lineages are GRHL1_T208, SCEL, and A2ML1. Each is linked with PRSS27 in more than 4 cancer types. Because this analysis shows association rather than direction, both PRSS27-to-partner and partner-to-PRSS27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRSS27 versus GRHL1_T208 in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS27→partner) and Y-score (partner→PRSS27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GRHL1_T208 →	+1.061	+0.940	<.001	<.001	3	5
HNSC	SCEL →	+0.979	+1.310	<.001	<.001	3	4
LSCC	A2ML1 →	+1.077	+0.645	<.001	<.001	3	4
LUAD	CRABP2 →	+1.442	+0.363	<.001	<.001	3	4
LSCC	ANXA1 →	+0.673	+0.871	<.001	<.001	3	4
UCEC	LYPD3 →	+1.618	+0.741	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,974 associations by consensus.

PRSS27 vs GRHL1_T208 — LSCC

Explore this scatter interactively →