PRSS22

Across TCGA patient cohorts, PRSS22 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRSS22-associated genes across cancer lineages are DC. Each is linked with PRSS22 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRSS22-to-partner and partner-to-PRSS22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DC grouped by PRSS22-low versus PRSS22-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS22→partner) and Y-score (partner→PRSS22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DC →	+0.028	+3.326	.018	.009	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

DC by PRSS22 expression — UCEC

Explore this box plot interactively →