PRSS12

Across TCGA patient cohorts, PRSS12 protein abundance is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRSS12-associated genes across cancer lineages are CUL9, MRPL19, and CTDSPL2. Each is linked with PRSS12 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRSS12-to-partner and partner-to-PRSS12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRSS12 versus CUL9 in LSCC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS12→partner) and Y-score (partner→PRSS12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CUL9 →	+0.570	+1.931	.006	.004	3	1
LSCC	MRPL19 →	+1.112	+1.684	.004	.007	3	1
LSCC	CTDSPL2 →	+0.751	+1.158	.006	.009	3	1
LSCC	ZNF740 →	+0.700	+1.190	.001	.007	3	1
LSCC	CLHC1 →	+1.232	+1.618	.002	.009	3	1
LSCC	STK36 →	+0.731	+1.630	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

PRSS12 vs CUL9 — LSCC

Explore this scatter interactively →