PRSS12

Across TCGA cell cohorts, PRSS12 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,518 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PRSS12-associated GO terms across cancer lineages are Telomere assembly, Mitotic cytokinetic process, and Positive regulation of proteolysis. Each is linked with PRSS12 in more than 5 cancer types. Because this analysis shows association rather than direction, both PRSS12-to-partner and partner-to-PRSS12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere assembly grouped by PRSS12-low versus PRSS12-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS12→partner) and Y-score (partner→PRSS12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Telomere assembly →	-0.120	-2.284	.006	.006	3	6
OVARY	Mitotic cytokinetic process →	+0.073	+1.429	.007	.002	3	6
STOMACH	Positive regulation of proteolysis →	+0.117	+2.117	.001	<.001	3	6
BREAST	Epidermis development →	+0.113	+1.530	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of protein modification by small protein conjugation or removal →	+0.048	+1.576	.001	<.001	3	6
BONE	Regulation of endothelial cell migration →	+0.069	+2.391	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,518 associations by consensus.

Telomere assembly by PRSS12 expression — BONE

Explore this box plot interactively →