PRRX2

Across TCGA patient cohorts, PRRX2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,019 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PRRX2-associated proteins across cancer lineages are PDLIM4, C1R, and CTHRC1. Each is linked with PRRX2 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRRX2-to-partner and partner-to-PRRX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRRX2 versus PDLIM4 in CCRCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRX2→partner) and Y-score (partner→PRRX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PDLIM4 →	+0.756	+0.731	<.001	<.001	3	8
GBM	C1R →	+0.409	+0.508	<.001	.006	3	7
COAD	CTHRC1 →	+0.943	+0.885	<.001	<.001	3	7
HNSC	ANTXR1_S362 →	+0.514	+0.754	.002	.009	3	7
CCRCC	PCOLCE →	+0.879	+0.655	<.001	<.001	3	7
COAD	RCN3 →	+0.713	+1.198	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,019 associations by consensus.

PRRX2 vs PDLIM4 — CCRCC

Explore this scatter interactively →