PRRX1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PRRX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,871 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PRRX1-associated proteins across cancer lineages are LMCD1, FLNA, and SEC23A. Each is linked with PRRX1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PRRX1-to-partner and partner-to-PRRX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRRX1 versus LMCD1 in OV, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRX1→partner) and Y-score (partner→PRRX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVLMCD1 →+0.658+1.540<.001<.001310
OVFLNA →+0.645+2.187<.001<.001310
OVSEC23A →+0.396+1.779<.001<.00139
OVSH3PXD2B →+0.468+1.823<.001<.00139
LSCCHOOK1 →-0.504-1.235<.001<.00139
BRCAISLR →+0.783+1.158<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,871 associations by consensus.

PRRX1 vs LMCD1 — OV

Per-sample scatter of PRRX1 vs LMCD1 in OV (Pearson r = 0.61).

Explore this scatter interactively →

Exploration