PRRX1

Across TCGA patient cohorts, PRRX1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,426 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PRRX1-associated genes across cancer lineages are ADAMTS12, DDR2, and COL6A3. Each is linked with PRRX1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRRX1-to-partner and partner-to-PRRX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRRX1 versus ADAMTS12 in OV, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRX1→partner) and Y-score (partner→PRRX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ADAMTS12 →	+1.682	+0.849	<.001	<.001	3	8
OV	DDR2 →	+2.017	+1.078	<.001	<.001	3	8
OV	COL6A3 →	+1.887	+0.893	<.001	<.001	3	8
UCEC	BNC2 →	+1.093	+0.431	<.001	<.001	3	8
UCEC	MSRB3 →	+1.248	+0.528	<.001	<.001	3	8
OV	TIMP3 →	+1.708	+0.661	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,426 associations by consensus.

PRRX1 vs ADAMTS12 — OV

Explore this scatter interactively →