Across TCGA pan-cancer cohorts, PRRT4 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated PRRT4 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PRRT4 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PRRT4 expression acts as an unfavorable survival marker.

COAD and READ are the cancer types where PRRT4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	III,IV	0.159	0.692	.021	12	view →
READ	DFS	Median	All	0.162	0.720	.019	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: PRRT4 tumor-vs-normal RNA expression · all PRRT4 data types