Across TCGA patient cohorts, PRRT4 mutation is significantly associated with the RNA expression of many other genes, with 931 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRRT4-associated genes across cancer lineages are MIR6509, TAF9, and COX15. Each is linked with PRRT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRRT4-to-partner and partner-to-PRRT4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRT4→partner) and Y-score (partner→PRRT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	MIR6509 →	+0.451	+5.039	.004	.008	3	2
UCEC	TAF9 →	+0.642	+3.169	<.001	<.001	3	2
UCEC	COX15 →	+0.389	+3.223	.006	.009	3	2
UCEC	HAUS1 →	+0.549	+3.191	.003	.009	3	2
UCEC	MRPL39 →	+0.452	+4.258	.001	<.001	3	2
UCEC	EME1 →	+0.753	+2.743	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 931 associations by consensus.

Exploration

PRRT4 survival (RNA) · tumor vs normal (RNA) · all PRRT4 data types