Across TCGA cell cohorts, PRRT4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,987 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRRT4-associated GO terms across cancer lineages are U2-type prespliceosome assembly, Negative regulation of mRNA metabolic process, and Negative regulation of adaptive immune response. Each is linked with PRRT4 in more than 11 cancer types. Because this analysis shows association rather than direction, both PRRT4-to-partner and partner-to-PRRT4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRT4→partner) and Y-score (partner→PRRT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	U2-type prespliceosome assembly →	+0.127	+0.774	.002	<.001	3	11
BREAST	Negative regulation of mRNA metabolic process →	+0.077	+0.644	<.001	.009	2	12
OESOPHAGUS	Negative regulation of adaptive immune response →	-0.090	-0.462	.003	.006	3	10
SOFT_TISSUE	Negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains →	-0.084	-1.075	<.001	<.001	3	10
OESOPHAGUS	Nucleic acid catabolic process →	+0.071	+0.741	.001	.001	3	9
STOMACH	Regulation of potassium ion transmembrane transport →	-0.149	-0.924	.001	.006	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,987 associations by consensus.

Exploration

PRRT4 survival (RNA) · tumor vs normal (RNA) · all PRRT4 data types