PRRT3

Across TCGA patient cohorts, PRRT3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,765 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRRT3-associated genes across cancer lineages are SKP1, CXCR2, and MIR29B2CHG. Each is linked with PRRT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRRT3-to-partner and partner-to-PRRT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRRT3 versus SKP1 in BRCA, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRT3→partner) and Y-score (partner→PRRT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SKP1 →	+0.717	+1.013	<.001	<.001	3	2
CCRCC	CXCR2 →	+0.817	+1.423	<.001	<.001	3	2
BRCA	MIR29B2CHG →	+1.079	+1.022	.004	.001	3	2
BRCA	FNIP1 →	+0.496	+0.768	.002	.004	3	2
CCRCC	ATP5MGP3 →	+0.313	+1.238	.002	<.001	3	2
GBM	MAG →	+1.916	+0.326	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,765 associations by consensus.

PRRT3 vs SKP1 — BRCA

Explore this scatter interactively →